HELPING TO KEEP YOU ON YOUR PATH TO TARGET

Discover the benefits of an integrated HD system

At Baxter, we understand that not two clinics are the same and as a result, we aim to design total renal solutions that can deliver the right therapy, at the right time, for the right care setting. As an integrated HD system the AK 98 system is a key component to achieving this objective. As an integrated solution it may help you find the balance between patient outcomes and operational efficiency.

Integrated dialysis solutions

A holistic approach to
renal therapies

  • Consumables

    • Dialyzers

      • POLYFLUX

      • REVACLEAR

      • HDx therapy enabled by the THERANOVA dialyzer

    • Bloodlines

      • BL series

    • Concentrates

      • BiCart

      • SoftPac citrate

    • Ultrafilters

      • U9000

      • DIACLEAR

    • Disinfectants

      • CleanCart A

      • CleanCart C

  • Services & System

    • IT

      • Diamant

    • Clinical Services

      • Education

      • User training

    • Water System

      • CWP 800

      • WRO 300 H

    • Technical Services

      • Service contract

      • Technical training

  • Monitor & Features

The Polyflux Dialyzer

The versatile design of the Polyflux dialyzers helps improve solute clearance for diverse patient needs

  • Effective removal of middle molecules such as b2m and minimal loss of essential proteins throughout dialysis1-4
  • The dialyzers are designed to minimize the risk of clotting5
  • POLYAMIX membrane is designed for endotoxin retention5-7
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The Revaclear Dialyzer

The precise and carefully engineered membrane aids retention of essential proteins, delivers high performance and effective treatments, and is designed for enhanced biocompatibility1,2

  • Options can meet the majority of patients’ clearance needs3-5
  • Effectively clears small and middle molecules3,6,7
  • Reduced priming and rinseback volume may minimize the potential risk of sodium loading7-9*
  • * Compared to a larger dialyzer
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Introducing

HDx therapy enabled by
the THERANOVA dialyzer

HDx achieved through membrane innovation

  • Markedly greater clearances and interdialytic reduction ratios than regular HD
    — at ordinary blood flow rates1
  • Similar to greater removal in comparison to high-volume HDF1
  • Albumin removal limited to between 1 and 4 grams1

HDx — Performance

  • Higher permeability1
  • Enhanced selectivity by size exclusion3,4
  • A step closer to the natural kidney1
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BIOCOMPATIBLE AND ERGONOMIC BLOOD TUBING SYSTEMS

High-quality blood tubing sets help to meet your individual clinic and patient needs1

  • DEHP free and gamma sterilized blood tubing available
  • Color-coded connectors
  • All treatment modalities available, HD, SN and low body weight
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THE SOFTPAC citrate CONCENTRATE

SoftPac Citrate is an acetate-free concentrate with all the beneficial properties of citrate

  • Improved tolerance to treatment 1-8
  • Improved acid-base status 1,9
  • Less thrombogenic dialysis 1,10,11
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The u9000 Ultrafilter

Endotoxin-retention filter designed for producing ultrapure dialysis fluid with safe and simple blood control.

  • Central and essential step for preparation of ultrapure dialysis fluid – recommended by European Best Practice Guidelines36
  • High-performance membrane with endotoxin-retention properties37
  • Use of ultrapure dialysis fluid reduces erythropoietin resistance38
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THE BICART CARTRIDGE

Essential component of a system designed for ultrapure dialysis fluid to avoid treatment-related inflammation1-5

  • The convenience of bicarbonate powder
  • Easy to use
  • The all-purpose bicarbonate cartridge
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THE CLEANCART CARTRIDGE

With CleanCart A and CleanCart C cartridges, regular dialysis machine maintenance and disinfection assure proper dialysis machine function and requires less intensive machine operation from clinical staff

  • Less space for storage and less heavy lifting for staff compared to liquid disinfectant
  • Removes organic deposits, fats and proteins with weekly use of CleanCart A cartridge1
  • Removes precipitated calcium and magnesium salts with daily use of CleanCart C cartridge1
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The CWP 800 System

The CWP 800 system provides full heat disinfection with optimized running cost

  • Reverse Osmosis unit with high performing membranes
  • Full heat disinfection to reduce formation of biofilm1,2
  • No need for chemical agents
  • Optimized running cost3
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Simple and efficient water purification

The WRO 300 H reverse osmosis system is a powerful water purification unit for single hemodialysis patient operation

  • Automated procedures and diagnostics minimize patient and caregiver workflow
  • Compact, easy to handle and operate with low noise levels
  • Chemical disinfection
  • Automated shut-off at completion of disinfection
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References

Bicart

  1. Ward RA. Sem Dialysis 2004; 17:489–497
  2. Ebben P. James Trans Am Soc Artif Organs vol. XXXIII 1987
  3. Lonnemann G. Blood Purif 2004; 22:124–129
  4. Gordon S. et al, Pyrogenic Reactions in Patients Receiving Concentional, High-Efficiency, or High-Flux Hemodialysis Treatment with BiCarbonate Dialysate Containing High Concentration of Bacteria and Endotoxin J. Am. Soc. Nephrol. 1992;2:1436-1444
  5. Helmut Schiffl, High-Flux Dialyzers, Backfiltration, and Dialysis Fluid Quality, Department of Internal Medicine, University Hospital Munich, Campus Innestandt, Munich Germany, 2011

Bloodlines

  1. Internal data Test Report DQ-TR 11/2016

CleanCart

  1. Pancírová J. Bye bye chemical disinfection with canisters EDTNA_ERCA JOURNAL 201;27(3): 123-124

CWP 800 system

  1. Ragon A, et al. Microbiological evaluation of the efficiency of hot R.O water only used to disinfect hemodialysis water distribution loop in operation for 5 years, Clin Kidney J 2011,4, Suppl 2 Abstracts from the 48th ERA_EDTA Congress
  2. Baxter data on file. Nystrand R. Long Time follow up of microbial quality in a Gambro CWP WRO ROHH system 1(5) BT 130502 S. Bio-teq Nystrand Consulting
  3. Baxter data on file.

Polyflux

  1. Joyeux V, et al. Int J Artif Organs 2008; 31(11):928-936
  2. Krieter DH, et al. Artif Organs 2008; 32:547-554
  3. Ouseph R, et. Al. Nephrol Dial Transplant 2008;23:1704-1712
  4. Lonnemann G, et. Al. Clin Nephrol 2009; 72:170-176
  5. Ronco C, et al. Nephrol Dial Transplant 2003; 18(Suppl 7):vii10-vii20
  6. Hoenich NA, et al. ASAIO J 2000; 46:70-75
  7. Ertl T, et al. Blood Purif 2003; 21:358

Revaclear

  1. Data on file. May 2013. Nilsson LG, Beck W and Bosch J. REVACLEAR White Paper. (USMP/MG3/140052)
  2. Data on file. 2012. Biological and Chemical Evaluation Report in Accordance to GWIN 11-09
  3. Mauric A, et al. Poster presented at 50th ERA_EDTA congress. Istanbul (Turkey). 2013. (Poster SP401)
  4. Von Albertini, In-vivo measured b2m clearance in high-flux HD and HDF
  5. Poster presented at ERA-EDTA 2013 congress
  6. Data on file. 2015. Calculations performed using the Gambro dose calculator tool. EUMP/MG135/15-0001
  7. Bhimani JP, et al. Nephrol Dial Transplant 2010; 25:3990-3995
  8. Ronco C, et al. Nephrol Dial Transplant 2003; 18 (Suppl 7):vii10-vii20
  9. Thijssen S, et al. Contrib Nephrol 2011;171:84-91

Softpac

  1. Grundström G, Christensson A, Alquist M, et al. Replacement of acectate with citrate in dialysis fluid: a randomized clinical trial of short term safety and fluid biocompatibility. BMC Nephrology 2013; 14:216
  2. Bryland A, Wieslander A, Carlsson O et al. Citrate treatment reduces endothelial death and inflammation under hyperglycaemic conditions. Diab Vasc Dis Res 2012;9(1):42-51
  3. Huang S, Sandholm K, Jonsson N et al. Low concentrations of citrate reduce complement and granulocyte activation in vitro in human blood. Clin Kidney J (2014) 0: 1-7
  4. Guido G, Loiacono E, Serriello I et al. Citrate-based dialysis buffers are more biocompatible in comparison to standard bicarbonate buffers and could prevent the progression of dialysis vasculopathy. Nephrol Dial Transplant 2013;28 (suppl1):i490
  5. Sjöberg B, Qureshi AR, Anderstam B et al. Pentraxin 3, a sensitive early marker of hemodialysis-induced inflammation. Blood Purif 2012;34(3-4):290-7
  6. Matsuyama K, Tomo T, Kadota J. Acetate-free blood purification can impact improved nutritional status in hemodialysis patients. J Artif Organs 2011;14(2):112-9
  7. Daimon S, Dan K, Kawano M. Comparison of acetate-free citrate hemodialysis and bicarbonate hemodialysis regarding the effect of intra-dialysis hypotension and post-dialysis malaise. Ther Apher Dial 2011;15(5):460-5
  8. Amore A, Cirina P, Bonaudo R et al. Bicarbonate dialysis, unlike acetate-free biofiltration, triggers mediators of inflammation and apoptosis in endothelial and smooth muscle cells. J Nephrol 2006;19(1):57-64
  9. Kuragano T, Kida A, Furuta M et al. Effects of acetate-free citrate-containing dialysate on metabolic acidosis, anemia, and malnutrition in hemodialysis patients. Artif Organs 2012;36(3):282-90

Theranova

  1. Boschetti-de-Fierro A, et al. MCO membranes: Enhanced Selectivity in High-Flux class. Scientific Reports (2015); 5: 18448
  2. Krause B, et al. Highly Selective membranes for blood purification. Euromembrane Congress 2015, Abstract E139
  3. Krause B, et al. Polymeric Membranes for Medical Applications. Chemie Ingenieur Technik (2003); 75 (11): 1725-1732
  4. Nilsson LG, Beck W and Bosch J. Data on File. White Paper May 2013 (USMP/MG3/140052)
  5. Kirsch AH et al. Performance of hemodialysis with novel medium cut-off dialyzers. Nephrol. Dial. Transplant. first published online September 1, 2016 doi:10.1093/ndt/gfw310
  6. Krieter D, et al. Clinical Performance of Medium Cutoff Hemodialysis versus High-Flux Hemodialysis and High-Volume Hemodiafiltration. ERA-EDTA 2016, Abstract MP46410.
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